The facts on very high triglycerides.

Approximately 4 million Americans have very high triglycerides.

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What are triglycerides?

Like cholesterol, triglycerides are naturally occurring fats in your blood used by the body in normal amounts to ensure good health—but they aren’t the same. Cholesterol is important for your cells and makes some hormones. Triglycerides store unused calories to give your body energy. However, very high levels of cholesterol or triglycerides may lead to serious health problems.1

Triglyceride levels are defined as follows:

  • Normal 
    less than 150 mg/dL
  • Borderline-high 
    150 to 199 mg/dL
  • High 
    200 to 499 mg/dL
  • Very high 
    500 mg/dL or higher

1NIH MedlinePlus Cholesterol 2018, NIH MedlinePlus Triglycerides Test 2017.

Man exercising at gym

How to lower very high triglyceride levels.

You can lower very high triglycerides with exercise, a healthier diet and talking to your doctor about adding prescription VASCEPA® to your daily routine.

What are the causes?

From a high carbohydrate diet to lack of exercise, there are many causes of very high triglycerides. Here are some ways that triglyceride levels may become very high:

Poor Diet


What you eat and drink affects your triglyceride level, especially alcohol and processed carbohydrates.

Lack of Exercise

Lack of Exercise

Not burning as many calories as you take in may have an impact on your triglycerides.

Medical Conditions

Medical Conditions

Health conditions, such as diabetes, change how your body processes food.

Specific Drugs

Specific Drugs

Drugs, including estrogen tablets and blood pressure medications.



People with a family history of very high triglycerides may be more likely to develop them.


How VASCEPA can help.

VASCEPA, along with diet, is clinically proven to lower very high triglycerides in adults by 33%, without raising bad cholesterol (LDL-C).*

It’s FDA-approved
to lower very high triglyceride levels.

Learn More

*In MARINE trial, on average, along with diet changes, adults with very high triglycerides experienced a 33% reduction without raising LDL-C vs. placebo. Individual results may vary.

Patient talking to doctor about VASCEPA

Ask your doctor if VASCEPA is right for you.

VASCEPA, along with diet and exercise, could be part of the solution to lowering very high triglycerides.

Here are some questions to help make the most of your next doctor visit.

Join The VASCEPA Clear Path Program.

Sign up today to receive motivational tips and useful information to support you on a Clear Path toward lowering very high triglycerides.


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VASCEPA is a prescription medicine used along with a low-fat and low-cholesterol diet to lower high levels of triglycerides (fats) in adults.

  • It is not known if VASCEPA changes your risk of having inflammation of your pancreas (pancreatitis).
  • It is not known if VASCEPA prevents you from having a heart attack or stroke.
  • It is not known if VASCEPA is safe and effective in children.



  • Do not take VASCEPA if you are allergic to icosapent ethyl or any of the ingredients in VASCEPA.


  • It is not known if people who are allergic to fish or shellfish are also allergic to VASCEPA.
  • If you have liver problems and are taking VASCEPA, your doctor should do blood tests during treatment.
  • The most common side effect of VASCEPA is joint pain. Talk to your doctor for medical advice about side effects.

As with all drugs, you may experience a serious side effect when taking VASCEPA.

You may report side effects by calling 1-855-VASCEPA or the FDA at 1-800-FDA-1088.

Tell your doctor if you take medicines that affect your blood clotting (anticoagulants or blood thinners).

Take VASCEPA capsules whole. Do not break, crush, dissolve, or chew VASCEPA capsules before swallowing.

For more information on VASCEPA, click here to see the full Patient Information or call 1-855-VASCEPA (1-855-827-2372).