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Discover what makes VASCEPA different

If you’re wondering what makes VASCEPA stand apart from other medications, we have answers.

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What’s in VASCEPA?

Cardio protection. Proven by science.

FDA-approved VASCEPA is made up of one active ingredient: icosapent ethyl (IPE), which is an innovative form of EPA.

If “EPA” sounds familiar, that’s because it’s an Omega-3 fatty acid. IPE is the only active ingredient in VASCEPA and is considered the reason behind the significant cardiovascular benefits VASCEPA can deliver.

How VASCEPA reduces cardiovascular risk.

VASCEPA is the first and only FDA-approved medication to lower CV risk in addition to other medications, such as statins, in patients with heart disease or diabetes and other risk factors. The exact science of how VASCEPA works in your body is not fully understood, but years of clinical testing have led to proven results. Ask your doctor about heart protection with VASCEPA.

Woman holding the clear VASCEPA® (icosapent ethyl) heart

Are you at greater risk than you think?

VASCEPA does more than triglyceride-lowering medications.

VASCEPA helps protect you from a life-threatening or debilitating event like a heart attack or stroke.

Medications like fenofibrates and niacin may lower your triglycerides but using them in addition to a statin did not reduce risk.

High triglycerides (over 150 mg/dL) can increase your odds of having a heart attack or stroke. VASCEPA is the first and only FDA-approved medicine to lower risk, when used with a statin, in patients with high triglycerides and heart disease or diabetes with other CV risk factors.

Woman holding the clear VASCEPA® (icosapent ethyl) heart

VASCEPA is different from fenofibrates and niacin.

  • Fenofibrates (TRILIPIX) and niacin (e.g., NIASPAN) are triglyceride-lowering treatments. They are not FDA approved to be used with statins to reduce CV risk, due to lack of CV benefit and more risk of a serious side effect that can lead to muscle breakdown in the body
  • It’s important to note that fenofibrates and niacin didn’t show additional CV benefit when used with statins in clinical studies, and were deemed by the FDA to have more risk than benefit when prescribed with statins. The FDA even removed the indication for these products to be used with statins
  • The American Diabetes Association also warned against using niacin and fenofibrates with statins, saying that the combination is not generally recommended due to added risks

A closer look at fish oil supplements

When it comes to protecting your heart, it’s important to know how fish oil supplements are different from VASCEPA.

Fish oil supplements

  • After reviewing decades of research, the FDA denied certain medical claims, like lowering blood pressure, for fish oil dietary supplements in 2019
  • Contain a mixture of ingredients that may be harmful to heart health, and may have a pronounced fishy smell or require smell masking to hide the signs of deterioration/oxidation (rotting)
  • Not intended or approved to treat heart disease
  • The American Heart Association advises against self-medicating with supplements
  • The most expensive product is one that doesn't treat the intended condition.

VASCEPA

  • Proven CV benefit in the landmark REDUCE-IT® trial
  • Made up of one active ingredient: IPE (icosapent ethyl), an innovative form of EPA
  • FDA approved to significantly reduce CV risk in patients taking statins. If you cannot take statins, talk to your doctor about whether or not VASCEPA can help you
  • Recognized by medical societies to lower CV risk in patients with heart disease or diabetes and risk factors

When it comes to protecting your heart, the choice is clear: FDA-approved VASCEPA.

VASCEPA® (icosapent ethyl) savings card

Looking for ways to save on VASCEPA?

VASCEPA is FDA-approved to help protect you from a life-threatening heart attack or stroke. Is VASCEPA right for you?

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INDICATIONS
WHAT IS VASCEPA?
VASCEPA is a prescription medicine used:
  • along with certain medicines (statins) to reduce the risk of heart attack, stroke and certain types of heart issues requiring hospitalization in adults with heart (cardiovascular) disease, or diabetes and 2 or more additional risk factors for heart disease.
  • along with a low-fat and low-cholesterol diet to lower high levels of triglycerides (fats) in adults.

It is not known if VASCEPA changes your risk of having inflammation of your pancreas (pancreatitis).
It is not known if VASCEPA is safe and effective in children.

IMPORTANT SAFETY INFORMATION
WHO SHOULD NOT TAKE VASCEPA?
  • Do not take VASCEPA if you are allergic to icosapent ethyl or any of the ingredients in VASCEPA.
What are the possible side effects of VASCEPA?
VASCEPA may cause serious side effects, including:
  • Heart rhythm problems (atrial fibrillation and atrial flutter). Heart rhythm problems which can be serious and cause hospitalization have happened in people who take VASCEPA, especially in people who have heart (cardiovascular) disease or diabetes with a risk factor for heart (cardiovascular) disease, or who have had heart rhythm problems in the past. Tell your doctor if you get any symptoms of heart rhythm problems such as feeling as if your heart is beating fast and irregular, lightheadedness, dizziness, shortness of breath, chest discomfort or you faint.
  • Possible allergic reactions if you are allergic to fish or shellfish. Stop taking VASCEPA and tell your doctor right away or get emergency medical help if you have any signs or symptoms of an allergic reaction.
  • Bleeding. Serious bleeding can happen in people who take VASCEPA. Your risk of bleeding may increase if you are also taking a blood thinner medicine.
If you have liver problems and are taking VASCEPA, your doctor should do blood tests during treatment.
The most common side effects of VASCEPA include:
  • Muscle and joint pain
  • Swelling of the hands, legs, or feet
  • Constipation
  • Gout
  • Heart rhythm problems (atrial fibrillation)
These are not all the possible side effects of VASCEPA. Call your doctor for medical advice about side effects. You may report adverse events (i.e. side effects) or product complaints by calling 1-855-VASCEPA (1-855-827-2372), emailing [email protected], or calling the FDA at 1-800-FDA-1088.

Tell your doctor if you take medicines that affect your blood clotting (anticoagulants or blood thinners).

For more information on VASCEPA, click here to see the full Patient Information or call 1-855-VASCEPA (1-855-827-2372).