Man holding a clear VASCEPA® (icosapent ethyl) heart

Let’s talk about diabetes, heart disease, and CV risk reduction.

Did you know adults with diabetes are 2x more likely to have a heart attack or stroke? If you have diabetes or heart disease, read on to see how VASCEPA may help protect your heart.

Managing diabetes &
cardiovascular (CV) risk.

First things first. VASCEPA is not a diabetes medication. It's very important to continue taking your medication as directed by your doctor.

VASCEPA is an FDA-approved, prescription medicine that can give your heart added protection when taken with a statin.

VASCEPA can help manage your CV risk if you have diabetes or heart disease. That risk can be persistent and often elevated, especially since you may not realize just how at risk you may be.

In a recent survey of people age 45 and older with type 2 diabetes, only half recognize or have discussed their risk for heart attacks or strokes with their healthcare providers.

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Doctor holding a clear VASCEPA® (icosapent ethyl) heartDoctor holding a clear VASCEPA® (icosapent ethyl) heart

There’s no such thing as too much heart protection.

The question for your doctor shouldn’t be “do I have enough heart protection?” It should be “how can I get additional heart protection?”

That’s where VASCEPA can help. If you have heart disease or diabetes and raised triglycerides (≥150 mg/dL), VASCEPA can help lower your chance of a life-threatening heart attack or stroke by 25% when added to a statin.*

*In a clinical study, patients treated with VASCEPA had fewer cardiovascular events (17.2%) compared to those who took placebo (22%).

An “A” from the ADA!

In Standards of Medical Care in Diabetes for 2019, the American Diabetes Association (ADA) gave icosapent ethyl, marketed as VASCEPA, an "A" recommendation.

What does that mean? Generally, the ADA felt that the large clinical trial conducted with VASCEPA was well-designed and produced results that should be considered by physicians treating those with diabetes and cardiovascular (CV) disease or other CV risk factors on a statin with controlled bad cholesterol and elevated triglyceride levels.

In adults with diabetes and other risk factors, VASCEPA can make a heart health difference when added to a statin.

The “A” recommendation from ADA was based on the quality of the REDUCE-IT® trial and is not for comparison to other diabetes products.

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Doctor talking with his patient

Ready to ask your doctor about VASCEPA? This guide can help you start the conversation.


Register for the VASCEPA Savings Program by entering your mobile number below or texting VASCEPA to 26789




VASCEPA is a prescription medicine used:

  • along with certain medicines (statins) to reduce the risk of heart attack, stroke and certain types of heart issues requiring hospitalization in adults with heart (cardiovascular) disease, or diabetes and 2 or more additional risk factors for heart disease.
  • along with a low-fat and low-cholesterol diet to lower high levels of triglycerides (fats) in adults.

It is not known if VASCEPA changes your risk of having inflammation of your pancreas (pancreatitis).
It is not known if VASCEPA is safe and effective in children.



  • Do not take VASCEPA if you are allergic to icosapent ethyl or any of the ingredients in VASCEPA.

What are the possible side effects of VASCEPA?
VASCEPA may cause serious side effects, including:

  • Heart rhythm problems (atrial fibrillation and atrial flutter). Heart rhythm problems which can be serious and cause hospitalization have happened in people who take VASCEPA, especially in people who have heart (cardiovascular) disease or diabetes with a risk factor for heart (cardiovascular) disease, or who have had heart rhythm problems in the past. Tell your doctor if you get any symptoms of heart rhythm problems such as feeling as if your heart is beating fast and irregular, lightheadedness, dizziness, shortness of breath, chest discomfort or you faint.
  • Possible allergic reactions if you are allergic to fish or shellfish. Stop taking VASCEPA and tell your doctor right away or get emergency medical help if you have any signs or symptoms of an allergic reaction.
  • Bleeding. Serious bleeding can happen in people who take VASCEPA. Your risk of bleeding may increase if you are also taking a blood thinner medicine.
If you have liver problems and are taking VASCEPA, your doctor should do blood tests during treatment.
The most common side effects of VASCEPA include:
  • Muscle and joint pain
  • Swelling of the hands, legs, or feet
  • Constipation
  • Gout
  • Heart rhythm problems (atrial fibrillation)
These are not all the possible side effects of VASCEPA. Call your doctor for medical advice about side effects. You may report adverse events (i.e. side effects) or product complaints by contacting AmarinConnect at 1-855-VASCEPA (1-855-827-2372), emailing [email protected], or calling the FDA at 1-800-FDA-1088.

Tell your doctor if you take medicines that affect your blood clotting (anticoagulants or blood thinners).

For more information on VASCEPA, click here to see the full Patient Information or call 1-855-VASCEPA (1-855-827-2372).